Ellen Pompeo Dr. Meredith Grey Actor Patrick Dempsey Dr. Derek Shepherd Actor Sandra Oh Dr. Cristina Yang Actor Katherine Heigl Dr. Izzie Stevens Actor Justin Chambers Dr. Alex Karev Actor T.R. Knight Dr. George O'Malley Actor Chandra Wilson Dr. Miranda Bailey Actor James Pickens Jr. Dr. Richard Webber Actor Sara Ramirez Dr. Callie Torres Actor Eric Dane Dr. Mark Sloan Actor Chyler Leigh Dr. Lexie Grey Actor Kevin McKidd Owen Hunt Guest Star Brandon Scott Guest Star Candice Afia Guest Star Mark Saul Guest Star Amrapali Ambegaokar Guest Star Gloria Garayua Guest Star Molly Kidder Guest Star Winston Story Guest Star Joseph Williamson Guest Star Shonda Rhimes Executive Producer Mark Gordon Executive Producer Betsy Beers Executive Producer James D. Parriott Executive Producer Jenna Bans Writer Tony Phelan Writer Stacy McKee Writer Mark Wilding Writer Debora Cahn Writer Krista Vernoff Writer William Harper Writer Peter Nowalk Writer Rob Corn Director Randy Zisk Director Joan Rater Writer Eric Stoltz Director Arlene Sanford Director Allison Liddi-Brown Writer Ed Ornelas Director Tom Verica Director