Ellen Pompeo Dr. Meredith Grey Actor Patrick Dempsey Dr. Derek Shepherd Actor Sandra Oh Dr. Cristina Yang Actor Katherine Heigl Dr. Izzie Stevens Actor Justin Chambers Dr. Alex Karev Actor Chandra Wilson Dr. Miranda Bailey Actor James Pickens Jr. Dr. Richard Webber Actor Sara Ramirez Dr. Callie Torres Actor Eric Dane Dr. Mark Sloan Actor Chyler Leigh Dr. Lexie Grey Actor Kevin McKidd Owen Hunt Actor Jessica Capshaw Dr. Arizona Robbins Actor Jeff Perry Thatcher Grey Guest Star Ralph Waite Irving Waller Guest Star Tom Amandes Tom Waller Guest Star Isabella Hofmann Irene Waller Guest Star Jocko Sims Randy Helsby Guest Star Kristen Ariza Angela Guest Star Mark Saul Intern Steve Guest Star Phil Abrams Dr. Nelson Guest Star Payton Silver Dr. Knox Guest Star Ursula Whittaker Angry Attending #1 Guest Star Shonda Rhimes Executive Producer Mark Gordon Executive Producer Betsy Beers Executive Producer James D. Parriott Executive Producer Jenna Bans Writer Tom Verica Director