Rachel Bilson Dr. Zoe Hart Actor Jaime King Lemon Breeland Actor Wilson Bethel Wade Kinsella Actor Cress Williams Lavon Hayes Actor Scott Porter George Tucker Actor Nadine Velazquez Didi Ruano Guest Star Tim Matheson Dr. Brick Breeland Guest Star Eisa Davis Addy Pickett Guest Star Penny Balfour Polly Parker Guest Star Deborah S. Craig Shelley Ng Guest Star Ilene Graff Mrs. Tucker Guest Star Christina DeRosa Waitress Guest Star Kevin Railsback Fred Sawaya Guest Star Judith Drake Elderly Woman Guest Star Leila Gerstein Executive Producer Josh Schwartz Executive Producer Stephanie Savage Executive Producer Len Goldstein Executive Producer Jason Ensler Executive Producer David Paymer Director Rina Mimoun Writer