Rachel Bilson Dr. Zoe Hart Actor Jaime King Lemon Breeland Actor Wilson Bethel Wade Kinsella Actor Cress Williams Lavon Hayes Actor Scott Porter George Tucker Actor Tim Matheson Dr. Brick Breeland Actor Kaitlyn Black AnnaBeth Nass Actor Josh Cooke Joel Stephens Guest Star Mircea Monroe Tansy Truitt Guest Star McKaley Miller Rose Hattenbarger Guest Star Peter Mackenzie Reverend Peter Mayfair Guest Star Steven M. Porter Frank Moth Guest Star Antoinette Robertson Lynly Haye Guest Star Brandi Burkhardt Crickett Watts Guest Star Mallory Moye Wanda Long Guest Star Ross Philips Tom Long Guest Star Charlie Robinson Sergeant Jeffries Guest Star John Marshall Jones Wally Maynard Guest Star Reginald VelJohnson Dash DeWitt Guest Star Christopher Curry Earl Guest Star John Eric Bentley Sheriff Bill Guest Star Karla Mosley Elodie Guest Star Matt Lowe Meatball Guest Star Armelia McQueen Shula Guest Star Carla Renata Susie Guest Star Kerry O'Malley Mrs. Mayfair Guest Star Reggie Hayes Don Todd Guest Star Annie Korzen Elderly Patient Guest Star Leila Gerstein Executive Producer, Writer Josh Schwartz Executive Producer Stephanie Savage Executive Producer Len Goldstein Executive Producer Jason Ensler Executive Producer Bethany Rooney Director