Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Omar Epps Dr. Eric Foreman Actor Jesse Spencer Dr. Robert Chase Actor Robin Tunney Rebecca Adler Guest Star Rekha Sharma Melanie Landon Guest Star Andrew Airlie Orange Colored Patient Guest Star Maya Massar Asthma Mom Guest Star Dylan Basu Asthma Boy Guest Star Ava Hughes Sydney Guest Star Kyarra Willis Kid 2 Guest Star Ethan Kyle Gross Molnar Guest Star Candus Churchill Substitute Teacher Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer, Writer Bryan Singer Executive Producer, Director