Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Omar Epps Dr. Eric Foreman Actor Jesse Spencer Dr. Robert Chase Actor Chi McBride Edward Vogler Guest Star Jennifer Stone Jessica Simms Guest Star Cynthia Ettinger Mrs. Simms Guest Star Susan Slome Lucille Hernandez Guest Star Ramon Franco Mr. Hernandez Guest Star Teddy Lane Jr. Mr. Conroy Guest Star Austin Leisle Seth Guest Star Karen Starc Mrs. Ayers Guest Star Alyson Morgan Clementine Guest Star Rose Colasanti Cashier Guest Star Alec George Classmate 1 Guest Star DJ Evans Classmate 2 Guest Star Bryan Fabian Classmate 3 Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Fred Gerber Director Thomas L. Moran Writer