Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Robert Sean Leonard Dr. James Wilson Actor Omar Epps Dr. Eric Foreman Actor Jesse Spencer Dr. Robert Chase Actor Peter Jacobson Dr. Chris Taub Actor Olivia Wilde Thirteen, Dr. Remy Hadley Actor Amber Tamblyn Martha M. Masters Guest Star Candice Bergen Arlene Cuddy Guest Star Matthew Lillard Jack Guest Star Jennifer Crystal Foley Rachel Taub Guest Star Kayla Colbert Rachel Cuddy Guest Star Rylie Colbert Rachel Cuddy Guest Star Shyloh Oostwald Daisy Guest Star Sprague Grayden Eva Guest Star Julie Mitchell Chloe Guest Star Nate Witty Bike Messenger Guest Star Rosalyn Sidewater Woman in Suit Guest Star Thai Douglas Conductor Guest Star Bobbin Bergstrom Nurse Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Miguel Sapochnik Director Sara Hess Writer