Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Robert Sean Leonard Dr. James Wilson Actor Omar Epps Dr. Eric Foreman Actor Jesse Spencer Dr. Robert Chase Actor Peter Jacobson Dr. Chris Taub Actor Olivia Wilde Thirteen, Dr. Remy Hadley Actor Amber Tamblyn Martha M. Masters Guest Star Kayla Colbert Rachel Cuddy Guest Star Rylie Colbert Rachel Cuddy Guest Star Nigel Gibbs Sanford Wells Guest Star Sasha Roiz Driscoll Guest Star Tyler James Williams Landon Guest Star Kyle Fain MacDonald Guest Star Rachel Melvin Wynn Guest Star Stella Maeve Kenzie Guest Star Kayla Ewell Nika Guest Star Maite Schwartz Bree Guest Star Grace Rowe School Director Guest Star Elizabeth A. Roberts Teacher Guest Star Patrick Rafferty Trucker Guest Star Melanie Cruz ER Doc Guest Star Turner Dixon Delivery Guy Guest Star Bobbin Bergstrom Nurse Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer David Straiton Director Liz Friedman Writer