Hugh Laurie Dr. Gregory House Actor Robert Sean Leonard Dr. James Wilson Actor Omar Epps Dr. Eric Foreman Actor Jesse Spencer Dr. Robert Chase Actor Peter Jacobson Dr. Chris Taub Actor Odette Annable Dr. Jessica Adams Actor Charlyne Yi Dr. Chi Park Actor Channon Roe Emory Guest Star Madison Davenport Iris Guest Star Julie McNiven Mickey Darro Guest Star Sarah Aldrich Faye Guest Star Robert Pine Mickey's Father Guest Star David Wells Milton Guest Star Alex Quijano Ray Guest Star Jeff Doba Gene Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Miguel Sapochnik Director David Hoselton Writer