Ryan Eggold Dr. Max Goodwin Actor Freema Agyeman Dr. Helen Sharpe Actor Janet Montgomery Dr. Lauren Bloom Actor Jocko Sims Dr. Floyd Reynolds Actor Tyler Labine Dr. Iggy Frome Actor Alejandro Hernández ED Nurse Casey Acosta Guest Star Keren Lugo Dr. Diana Flores Guest Star Megan Byrne Gladys Guest Star Shiva Kalaiselvan ED Resident Leyla Shinwari Guest Star Debra Monk Chairwoman Karen Brantley Guest Star Matthew Jeffers ED Chief Resident Dr. Mark Walsh Guest Star Andre Blake Dr. Claude Baptiste Guest Star Jennifer Betit Yen OR Nurse Aimee Kamoe Guest Star Genevieve Angelson Dr. Mia Castries Guest Star Michelle Forbes Dr. Veronica Fuentes Guest Star Olivia Khoshatefeh Dr. Yasmin Turan Guest Star Christine Chang Dr. Agnes Kao Guest Star Frances Turner Dr. Lyn Malvo Guest Star Sandra Mae Frank Dr. Elizabeth Wilder Guest Star Conner Marx Ben Guest Star David Schulner Executive Producer, Writer Peter Horton Executive Producer Michael Slovis Executive Producer, Director David Foster Executive Producer, Writer Aaron Ginsburg Executive Producer, Writer Shaun Cassidy Executive Producer, Writer Darnell Martin Director Rachel Leiterman Director Nestor Carbonell Director Nick Gomez Director Lisa Robinson Director Laura Valdivia Writer Graham Norris Writer Marc Gaffen Writer Brandy E. Palmer Writer