Linda Wallem Creator Liz Brixius Creator Evan Dunsky Creator Edie Falco Jackie Peyton Actor Eve Best Dr. O'Hara Actor Peter Facinelli Dr. Cooper Actor Merritt Wever Zoey Actor Paul Schulze Eddie Actor Anna Deavere Smith Gloria Akalitus Actor Dominic Fumusa Kevin Peyton Actor Bobby Cannavale Mike Cruz Actor Ruby Jerins Grace Peyton Actor Mackenzie Aladjem Fiona Peyton Actor Stephen Wallem Thor Lundgren Actor Arjun Gupta Sam Actor Lenny Jacobson Lenny Actor Laura Silverman Laura Guest Star Billie Joe Armstrong Jackie's Pickup Guest Star Brad Fleischer Dustin Guest Star Caryn Mandabach Executive Producer Jesse Peretz Director