Christina Applegate Samantha Actor Jennifer Esposito Andrea Belladonna Actor Kevin Dunn Howard Actor Melissa McCarthy Dena Actor Tim Russ Frank Actor Barry Watson Todd Actor Jean Smart Regina Newly Actor Kelsey Smith Young Samantha Guest Star Dean Cochran Guest Star Joy Lofton Hypnotherapist Guest Star Donald Todd Executive Producer Peter Traugott Executive Producer Pamela Ribon Writer Michael Alan Spiller Director