Zach Braff Dr. John "J.D." Dorian Actor Sarah Chalke Dr. Elliott Reid Actor Donald Faison Dr. Chris Turk Actor John C. McGinley Dr. Perry Cox Actor Judy Reyes Nurse Carla Espinosa Actor Ken Jenkins Dr. Bob Kelso Actor Neil Flynn The Janitor Actor Courteney Cox Dr. Maddox Guest Star Christa Miller Jordan Guest Star Betsy Beutler Katie Guest Star Jennifer Jostyn Dr. Simmons Guest Star Annie Little Christine Guest Star Frank Novak Pat Rosell Guest Star Marcus Folmar Mr. Tillman Guest Star Frank Cameron Dr. Mickhead Guest Star Bradley Charles Etheridge Medical Intern Guest Star Alan Mueting Gift Shop Patron Guest Star Cara Quici Nurse Guest Star Bill Lawrence Executive Producer Janae Bakken Writer Michael Alan Spiller Director