Johnny Galecki Leonard Hofstadter Actor Jim Parsons Sheldon Cooper Actor Kaley Cuoco Penny Actor Simon Helberg Howard Wolowitz Actor Kunal Nayyar Raj Koothrappali Actor Mayim Bialik Amy Farrah Fowler Guest Star Jessica Walter Mrs. Latham Guest Star Joshua Malina President Siebert Guest Star Chuck Lorre Executive Producer, Writer Bill Prady Executive Producer, Writer Lee Aronsohn Writer David Goetsch Writer Eric Kaplan Writer Steve Holland Writer Mark Cendrowski Director