Charlie Sheen Charlie Harper Actor Jon Cryer Alan Harper Actor Angus T. Jones Jake Harper Actor Holland Taylor Evelyn Harper Actor Conchata Ferrell Berta Actor Melanie Lynskey Rose Actor Jennifer Taylor Chelsea Guest Star Martin Mull Russell Guest Star Ronobir Lahiri Dr. Gollygupta Guest Star Katherine LaNasa Lydia Guest Star Ming-Na Wen Linda Guest Star Emmanuelle Vaugier Mia Guest Star Rachel Cannon Chloe Guest Star Aja Evans Emily Guest Star Magdalena Holland Svetlana Guest Star Rebecca McFarland Leanne Guest Star Katy Mixon Betsy Guest Star Jodi Lyn O'Keefe Isabella Guest Star Missi Pyle Delores Pasternak Guest Star Rena Sofer Chrissy Guest Star Nayo K. Wallace Paulina Guest Star Jennifer C. Sparks Danielle Guest Star Robert Clotworthy TV Announcer Guest Voice ZZ Top ZZ Top Guest Star Justine Eyre Gabrielle Guest Star Billy Gibbons Billy Gibbons Guest Star Dusty Hill Dusty Hill Guest Star Frank Beard Frank Beard Guest Star Chuck Lorre Executive Producer, Writer Lee Aronsohn Executive Producer, Writer Eric Tannenbaum Executive Producer Kim Tannenbaum Executive Producer Mark Burg Executive Producer Oren Koules Executive Producer Susan Beavers Writer David Richardson Writer Mark Roberts Writer Don Foster Writer Eddie Gorodetsky Writer Jim Patterson Writer James Widdoes Director