Jeremiah S. Chechik Director Chevy Chase Clark Wilhelm Griswold, Jr. Actor Beverly D'Angelo Ellen Griswold Actor Randy Quaid Cousin Eddie Johnson Actor Diane Ladd Nora Griswold Actor John Randolph Clark Wilhelm Griswold, Sr. Actor E.G. Marshall Art Smith Actor Doris Roberts Frances Smith Actor Julia Louis-Dreyfus Margo Chester Actor Mae Questel Aunt Bethany Actor William Hickey Uncle Lewis Actor Brian Doyle-Murray Mr. Frank Shirley Actor Juliette Lewis Audrey Griswold Actor Johnny Galecki Russell 'Rusty' Griswold Actor Nicholas Guest Todd Chester Actor Miriam Flynn Cousin Catherine Johnson Actor Ellen Latzen Cousin Ruby Sue Johnson Actor John Hughes Producer William S. Beasley Associate Producer Mauri Syd Gayton Associate Producer Tom Jacobson Producer Matty Simmons Executive Producer Ramey E. Ward Associate Producer Daniel Grodnik Executive Producer Angelo Badalamenti Original Music Thomas E. Ackerman Cinematographer Gerald B. Greenberg Film Editing Risa Bramon Garcia Casting Michael A. Stevenson Film Editing Billy Hopkins Casting Beala Neel Art Director Lisa Fischer Set Decoration Michael Kaplan Costume Design Stephen Marsh Production Design