Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Dr. Joan Watson Actor Aidan Quinn Capt. Tobias "Toby" Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Freda Foh Shen Mary Watson Guest Star Steve Park Oren Watson Guest Star Gbenga Akinnagbe Jeremy Lopez Guest Star Reg Rogers Micah Erlich Guest Star Dee Hoty Patsy Guest Star Nat McIntyre Uniform Guest Star Sue Simmons Reporter Guest Star Sean Dugan Charles Briggs Guest Star Tonya Glanz Gwen Guest Star Jennifer Kim Gabrielle Harper Guest Star Robert Doherty Executive Producer Sarah Timberman Executive Producer Carl Beverly Executive Producer Michael Cuesta Executive Producer Corinne Brinkerhoff Writer Craig Sweeny Writer Peter Werner Director