Goran Visnjic Dr. Luka Kovac Actor Maura Tierney Abby Lockhart Actor Mekhi Phifer Dr. Gregory Pratt Actor Parminder Nagra Dr. Neela Rasgotra Actor Linda Cardellini Nurse Samantha Taggart Actor Shane West Actor Scott Grimes Dr. Archie Morris Actor Laura Innes Dr. Kerry Weaver Actor John Stamos Dr. Tony Gates Actor Forest Whitaker Curtis Ames Guest Star Kip Pardue Ben Parker Guest Star Busy Philipps Hope Bobeck Guest Star Fred Ward Eddie Wyczenski Guest Star Malaya Rivera Drew Katey Alvaro Guest Star Michelle Hurd Courtney Brown Guest Star Sam Jones III Chaz Pratt Guest Star J.P. Manoux Dr. Dustin Crenshaw Guest Star Glenn Plummer Timmy Rawlins Guest Star Charlayne Woodard Angela Gilliam Guest Star Christopher Chulack Executive Producer Michael Crichton Executive Producer David Zabel Executive Producer John Wells Executive Producer R. Scott Gemmill Executive Producer