Blake Lively Serena van der Woodsen Actor Leighton Meester Blair Waldorf Actor Penn Badgley Dan Humphrey Actor Chace Crawford Nate Archibald Actor Ed Westwick Chuck Bass Actor Kaylee Defer Charlie Rhodes Actor Kelly Rutherford Lily van der Woodsen Actor Matthew Settle Rufus Humphrey Actor Michelle Trachtenberg Guest Star William Baldwin Guest Star Michael Michele Guest Star Desmond Harrington Guest Star Caroline Lagerfelt Guest Star Elizabeth Hurley Guest Star Ella Rae Peck Guest Star Taylor Momsen Jenny Humphrey Actor Hugo Becker Guest Star Elizabeth Quinn Brown Guest Star Sloane Crosley Guest Star Zoe Bell Guest Star Josh Schwartz Executive Producer Stephanie Savage Executive Producer Leslie Morgenstein Executive Producer Bob Levy Executive Producer Joshua Safran Executive Producer Mark Piznarski Director Andy Wolk Director Joe Lazarov Director Tate Donovan Director Andrew McCarthy Director Jake Coburn Writer Amanda Lasher Writer Austin Winsberg Writer Sara Goodman Writer Natalie Krinsky Writer Amy B. Harris Writer Matt Whitney Writer Peter Elkoff Writer J. Miller Tobin Director Bart Wenrich Director