Ellen Pompeo Dr. Meredith Grey Actor Patrick Dempsey Dr. Derek Shepherd Actor Sandra Oh Dr. Cristina Yang Actor Katherine Heigl Dr. Izzie Stevens Actor Justin Chambers Dr. Alex Karev Actor Chandra Wilson Dr. Miranda Bailey Actor James Pickens Jr. Dr. Richard Webber Actor Sara Ramirez Dr. Callie Torres Actor Eric Dane Dr. Mark Sloan Actor Chyler Leigh Dr. Lexie Grey Actor Kevin McKidd Owen Hunt Actor Jessica Capshaw Dr. Arizona Robbins Actor Shannon Lucio Guest Star Debra Monk Guest Star Martha Plimpton Guest Star Mitch Pileggi Guest Star Zoe Boyle Guest Star Zack Shada Guest Star Jim Metzler Guest Star Emily Roche Guest Star Payton Silver Guest Star Alicia Hannah Guest Star Mark Saul Guest Star Molly Kidder Guest Star Joseph Williamson Guest Star Winston Story Guest Star Gloria Garayua Guest Star Tymberlee Hill Guest Star Lori Yeghiayan Guest Star Ray Ford Guest Star Shonda Rhimes Executive Producer Mark Gordon Executive Producer Betsy Beers Executive Producer James D. Parriott Executive Producer Krista Vernoff Writer Ed Ornelas Director