Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Vicellous Reon Shannon Carnell Hall Guest Star Clifton Powell Ken Hall Guest Star Diane Baker Blythe House Guest Star R. Lee Ermey John House Guest Star Wil Horneff Taddy Guest Star Brian Johnson Taddy's Boss Guest Star Matt McKenzie Dr. Fedler Guest Star Bobbin Bergstrom Nurse Guest Star Jon Hershfield Timekeeper Guest Star Brian Chase E.M.T. Guest Star Mackenzie English Katrina Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Greg Yaitanes Director Thomas L. Moran Writer