Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Brian Klugman Stark Guest Star Anne Dudek Dr. Amber Volakis Guest Star Olivia Wilde Thirteen, Dr. Remy Hadley Guest Star Peter Jacobson Dr. Chris Taub Guest Star Kal Penn Dr. Lawrence Kutner Guest Star Carmen Argenziano Henry Dobson Guest Star Edi Gathegi Dr. Jeffrey 'Big Love' Cole Guest Star Andy Comeau Dr. Travis Brennan Guest Star Meera Simhan Dr. Jody Desai Guest Star Melinda Dahl Twin 15A Guest Star Caitlin Dahl Twin 15B Guest Star Charlie Hofheimer Mark Allmore Guest Star Kathleen York Dr. Schaffer Guest Star Mary Kate Schellhardt Female Fellow Guest Star Reynaldo Rosales Handsome Fellow Guest Star Douglas Spain Latino Fellow Guest Star Bobbin Bergstrom Nurse Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer David Platt Director Russel Friend Writer Garrett Lerner Writer