Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Robert Sean Leonard Dr. James Wilson Actor Omar Epps Dr. Eric Foreman Actor Jesse Spencer Dr. Robert Chase Actor Peter Jacobson Dr. Chris Taub Actor Olivia Wilde Thirteen, Dr. Remy Hadley Actor Amber Tamblyn Martha M. Masters Guest Star Dylan Baker Dr. Dave Broda Guest Star Cynthia Watros Sam Carr Guest Star Devon Woods Eve Guest Star Hayley Chase Julie Guest Star Samantha Smith Lulu Guest Star Aaron Refvem Roger Guest Star Leslie Murphy Natalie Guest Star Tess Kartel Geerte Guest Star Neil Sandilands Captain Vanderhoof Guest Star Daniel Colembie Dr. Trimingham Guest Star Demetrius Grosse Hacinte Guest Star Andrew Fiscella Niles Guest Star Bobbin Bergstrom Nurse Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Tucker Gates Director Lawrence Kaplow Writer