Damon Wayans Roger Murtaugh Actor Clayne Crawford Martin Riggs Actor, Director Kevin Rahm Captain Brooks Avery Actor Jordana Brewster Dr. Maureen "Mo" Cahill Actor Keesha Sharp Trish Murtaugh Actor Johnathan Fernandez Scorsese Actor Michelle Mitchenor Detective Bailey Actor Dante Brown Roger Murtaugh Jr. Actor Chandler Kinney Riana Murtaugh Actor Kristen Lee Gutoskie Molly Guest Star Andrew Patrick Ralston Jim McNeile Guest Star Todd Grinnell Jerry Guest Star Kristanna Loken Adriana Guest Star Ken Garito Nick Guest Star Michael Beach Bryan Graves Guest Star Paul Ben-Victor Frank Guest Star Frankie Jay Allison Paulie Guest Star Matt Miller Executive Producer McG Executive Producer Dan Lin Executive Producer Jennifer Gwartz Executive Producer Steve Boyum Director Omar Madha Director Eric Laneuville Director Salli Richardson-Whitfield Director Maja Vrvilo Director John Behring Director Larry Teng Director Silver Tree Director Nick Copus Director