The sixth-season opener of Murder She Wrote takes place in Athens, where mystery writer Jessica Fletcher (Angela Lansbury) is reunited with suave but inherently untrustworthy British secret agent Michael Haggerty (Len Cariou). In order to help Haggerty rescue a kidnapped fellow spy, Jessica reluctantly agrees to pose as Haggerty's wife. Before long, our heroine finds herself up to her neck in peril, especially after the authorities find a dead body in her hotel room.

Father Barnes (Hunt Block), a young Cabot Cove priest, refuses to reveal the words spoken by a parishioner during Confessional. It doesn't matter that the parishioner has confessed to killing a person in self-defense: Father Barnes is bound by the rules of his order, and remains mum. The situation gets worse when another person is accused of the killing, at which point Jessica Fletcher, bound by no rules other than her own, decides to intervene. This episode marks the first of several series appearances by Madlyn Rhue, an actress who had been forced into virtual retirement by multiple sclerosis, but who was able to pay her medical bills by occasionally appearing on Murder She Wrote through the auspices of her friend Angela Lansbury.

The death of Jessica's role model, Agatha Christie-like mystery novelist Lady Abigail Austin (June Havoc), sets Jessica (Angela Lansbury) to thinking of an incident back in 1947 in which Lady Abigail was involved in a real-life murder case. In an extended flashback, the action takes place on board the luxury liner "Queen Mary", where an ex-Gestapo officer has been stabbed to death--and Lady Abigail is the primary suspect. The presence of a father-son team of detectives (played by John Karlen and Gary Kroeger) suggests that this episode may have actually been intended for an earlier Richard Levinson-William Link TV mystery series, Ellery Queen.

Jessica (Angela Lansbury) accuses the wife of a Palm Springs real estate developer of murdering her philandering husband. Shortly thereafter, the accused woman commits suicide, and her sister bitterly accuses Jessica of driving the woman to her death. Teaming up with police detective Hanna (Elliott Gould), Jessica tries to find out if she indeed condemned an innocent person--and in the process, the two sleuths search high and low for the $3 million allegedly embezzled by the murder victim.

This time, the spotlight is on a friend of Jessica Fletcher (Angela Lansbury--namely, Bill Boyle (Ken Howard), a former football star turned detective. When Bill agrees to temporarily take care of a pal's valuable poodle, he ends up permanently saddled with the pooch when the owner is murdered, clutching three empty IV bags in his cold, dead fingers. It soon becomes clear that the murderers have now targeted both Bill and the poodle, plunging man and dog alike into a hotbed of international intrigue.

Purchasing an antique bureau at a furniture store rummage sale, Jessica finds an old, undelivered letter in one of the drawers. For reasons made clear in the episode, she turns the letter over to a local volunteer fireman (Jonathan Goldsmith)--who later perishes in a blaze that was deliberately set at the very same furniture store. Want to bet that the letter and the murder are somehow linked, and that Jessica will find that link before episode's end?

Jessica (Angela Lansbury) is off to Jamaica, there to visit an old friend living on a sprawling plantation. No sooner has she arrived than Jessica is plunged into family intrigue, stemming from the decision by the plantation heir to wed the daughter of an Obeah priest. This not only dashes the hopes of the family merging with another prosperous Jamaican plantation clan, but it also leads to murder--apparently the fulfillment of an ancient voodoo curse! Musical stage star Shani Wallis makes a rare American TV appearance in this episode.

Keith Michell returns in the role of Dennis Stanton, an ex-jewel thief turned insurance investigator. Jessica (Angela Lansbury) links up with her old friend Dennis when she arrives in San Francisco to attend the opening of a prestigious opera. Before long, things become "operatic" for real when a celebrated tenor, who had previously shot another man (in self-defense, he claimed) who'd been making overtures to the tenor's pretty protégée, succumbs to a suspicious heart attack.

Jessica (Angela Lansbury) is summoned to the island retreat of her friend Henry Reynard (Gene Barry), a millionaire lumberman. Someone has threatened Henry's life, and he is convinced that the "someone" is a relative anxious to get his or her hands on the old man's millions. Upon her arrival, Jessica is told that Henry has already been killed--but as she soon finds out, appearances (and first impressions) can be very deceiving!

The emphasis in this episode is not on Jessica (Angela Lansbury) but on her old friend, indefatigable LA homicide detective Jake Ballinger (Barry Newman). Refusing to give up his own personal investigation of a "closed" murder case, Jake is forcibly relocated to a small college town, there to teach a course in criminology. Of course, Ballinger intends to continue pursuing his investigation, this time with help of his students--all two of them (he'd scared the rest of the class away on the first day of the semester!)