Ryan Eggold Dr. Max Goodwin Actor Freema Agyeman Dr. Helen Sharpe Actor Janet Montgomery Dr. Lauren Bloom Actor Jocko Sims Dr. Floyd Reynolds Actor Tyler Labine Dr. Iggy Frome Actor Anupam Kher Dr. Vijay Kapoor Actor Mike Doyle Martin McIntyre Guest Star Larry Bryggman Dr. George Helms Guest Star Nora Clow Luna Guest Star Opal Clow Luna Guest Star Kerry Flanagan Marsha Guest Star Em Grosland ED Nurse Brunstetter Guest Star Emma Ramos ED Resident Mariana Guest Star Christine Chang Dr. Agnes Kao Guest Star Nadia Affolter Mina Jahani Guest Star Margot Bingham Evie Garrison Guest Star Anna Suzuki Sandra Fall Guest Star Stephen Spinella Howie Cournemeyer Guest Star Simone Policano Karla Guest Star Baylen Thomas Abbie Shumway Guest Star Andre De Shields Dale Rustin Guest Star Dierdre Friel Ella Guest Star Joshua Gitta Kwame Adu Guest Star Jamie Ann Romero Assistant Blood Bank Head Dr. Val Tiwari Guest Star David Schulner Executive Producer Peter Horton Executive Producer Michael Slovis Executive Producer David Foster Executive Producer Aaron Ginsburg Executive Producer Shaun Cassidy Executive Producer Darnell Martin Director Graham Norris Writer