Mardi Gras proves hectic for the responders; a man impales his hand on a fence, while another is stabbed in the face; the search for armed robbers leads to a high-speed chase.

A high-speed chase leads to a shootout with SWAT officers; a woman loses her eyeball in a fight; responders treat a shooting victim in a dangerous location; two men become involved in a violent knife fight.

Gavin and his new partner, Ted, travel to Bourbon Street to treat a woman with a broken ankle; the SWAT team serves a high-risk warrant; an accident victim's arm is cut to the bone; a man falls off a ladder and lands on a roof.

A beloved police officer is shot and killed while on duty; officers come under fire during an attempt to serve a warrant; a bicyclist's leg is mangled in an accident.

Titus and Dan assist a woman who was stabbed in the face; Holly and Nick tend to a transgender assault victim; a wild car chase ends with a major accident, firefighters work to put out a structure fire.

A woman stands to lose her arm following a bloody barroom brawl; a first responder is attacked while he attempts to provide aid at the scene of a car accident; a teenage bike thief receives some tough love.

New partners Arkady and Tom search for a victim who vanished in a river; a motorcyclist suffers serious injuries in an accident; a pedicab driver hurts his leg; a drug dealer hides out in a dangerous neighborhood.

The first responders work to save the victims of several shootings and a drug overdose; police officers apprehend suspects in possession of illegal firearms.

Police officer Justin joins the SWAT team in a raid; the first responders treat an accident victim with amnesia and a woman who fell off a roof; Arkady bonds with a man who attempted suicide.

Emergency medical technicians assist drug addicts and victims of assaults and accidents; police officers work to keep weapons off the streets.