Roseanne Barr Roseanne Conner Actor John Goodman Dan Conner Actor Alicia Goranson Becky Conner-Healy Actor Sara Gilbert Darlene Conner Actor Michael Fishman D.J. Conner Actor Laurie Metcalf Jackie Harris Actor Natalie West Crystal Anderson Conner Guest Star Bonnie Sheridan Bonnie Watkins Guest Star Sandra Bernhard Nancy Bartlett Thomas Guest Star Tom Arnold Arnie Thomas Guest Star Johnny Galecki Kevin Healy Guest Star David Crosby Duke Guest Star Paul Eisenhauer Frank Guest Star Michael Dempsey Ray Guest Star James Pickens Jr. Chuck Mitchell Guest Star Don Foster Writer Andrew Weyman Director