Dominic West Det. James "Jimmy" McNulty Actor John Doman William A. Rawls Actor Frankie Faison Comm. Ervin H. Burrell Actor Wood Harris Avon Barksdale Actor Domenick Lombardozzi Det. Thomas "Herc" Hauk Actor Deirdre Lovejoy Rhonda Pearlman Actor Wendell Pierce Det. William "Bunk" Moreland Actor Lance Reddick Lt. Cedric Daniels Actor Andre Royo Bubbles Actor Sonja Sohn Det. Shakima "Kima" Greggs Actor J.D. Williams Preston "Bodie" Broadus Actor Seth Gilliam Sgt. Ellis Carver Actor Clarke Peters Det. Lester Freamon Actor Jim True-Frost Det. Roland "Prezbo" Pryzbylewski Actor Michael Kenneth Williams Omar Little Actor Corey Parker Robinson Det. Leander Sydnor Actor Robert Wisdom Howard "Bunny" Colvin Actor Aidan Gillen Thomas "Tommy" Carcetti Actor Jamie Hector Marlo Stanfield Actor Chad L. Coleman Dennis "Cutty" Wise Actor Isiah Whitlock Jr. State Sen. R. Clayton "Clay" Davis Actor Glynn Turman Mayor Clarence V. Royce Actor Reg E. Cathey Norman Wilson Guest Star Jermaine Crawford Duquan "Dukie" Weems Guest Star Maestro Harrell Randy Wagstaff Guest Star Julito McCullum Namond Brice Guest Star Mack Wilds Michael Lee Guest Star Robert F. Chew Joseph "Proposition Joe" Stewart Guest Star Susan Duvall Assistant Principal Marcia Donnelly Guest Star Dravon James Grace Sampson Guest Star Edward Norris Det. Edward Norris Guest Star Michael Kostroff Maurice "Maury" Levy Guest Star Delaney Williams Sgt. Jay Landsman Guest Star Sam Coppola Former Mayor "Young Tony" Guest Star Gregory L. Williams Det. Michael Crutchfield Guest Star Brian Anthony Wilson Det. Vernon Holley Guest Star Cleo Reginald Pizana Chief of Staff Coleman Parker Guest Star Susan Rome Asst. State's Atty. Ilene Nathan Guest Star Frederick Strother State Delegate Odell Watkins Guest Star Stacie Davis Ms. Duquette Guest Star Dan DeLuca David Parenti Guest Star Dion Graham State's Attorney Rupert Bond Guest Star Greg Ainsworth Richard Switowski Guest Star Nathan Corbett Donut Guest Star Thuliso Dingwall Kenard Guest Star Edward Green Spider Guest Star Jeffrey Lorenzo Karim Williams Guest Star Daniel Lee Robertson III Shaun Williams Guest Star Tony Devon Mr. Shopper Guest Star Anthony Hemingway Director Ed Burns Writer William F. Zorzi Writer