Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Matt Hobby Pastor Jeff Actor Ryan Phuong Tam Guest Star Nancy Linehan Charles Peg Guest Star Mary Grill Officer Robin Guest Star Ed Begley Jr. Dr. Linkletter Guest Star Valerie Mahaffey Ms. Macelroy Guest Star Danielle Pinnock Ms. Ingram Guest Star Brian Stepanek Mr. Givens Guest Star Doc Farrow Coach Wilkins Guest Star Caleigh Kilpatrick Abigail Baker Guest Star Chuck Lorre Executive Producer, Writer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Steve Holland Writer Tara Hernandez Writer Jeremy Howe Writer Connor Kilpatrick Writer Alex Reid Director