Paul Seed Director Paul Reiser Dr. Jerry Lipman Actor Julie Walters Sheila Fitzpatrick Actor Amber Sealey Ellen Actor George Wendt Howard Actor Lachele Carl Sharna Actor Olympia Dukakis Esther Lipman Actor Catherine Porter Party Girl Actor Todd Boyce Oncologist Actor Mary Cunningham Mrs. Brailsford Actor Amy Robbins Maureen Actor Gregory Fossard Antony Actor Tony Maudsley Frank Actor Rowan Humphries Emma Actor Suzanne Hitchmough Mavis Actor Georgina Smith Auntie Vi Actor Ricky Tomlinson Uncle Alfred Actor Ian Puleston-Davies Derek Actor Christopher Wright UK Oncologist Actor Marcel Vormawah-Jones Hostel Boy Actor Lee Gilbert Hostel Boy Actor Kenny Thompson Lenny Actor Terry Gilbert Reggie Actor Stephanie Roscoe Neighbor No. 1 Actor David Heath Tony Actor Marie Higham Neighbor No. 2 Actor Gareth Turtle Bellboy Actor Sarah Baxendale Attending Nurse Actor Tim Kazurinsky Attending Nurse Actor, Writer Mark Lawrence Orderly Actor