Jennifer Garner Sydney Bristow Actor Victor Garber Jack Bristow Actor Ron Rifkin Arvin Sloane Actor Michael Vartan Michael Vaughn Actor Lena Olin Irina Derevko, Laura Bristow Actor Bradley Cooper Will Tiffin Actor Merrin Dungey Francie Calfo Actor Carl Lumbly Marcus Dixon Actor Kevin Weisman Marshall Flinkman Actor David Anders Julian Sark Actor Mark Ivanir Boris Oransky Guest Star Scott Adsit Pierre Lagravenese Guest Star Pierrino Mascarino Wcience Ministry Official Guest Star Elizabeth Penn Payne Carolyn Guest Star Arthur Darbinyan Ministry Official Guest Star Deeonna Lanay Young Girl Guest Star Patricia Rae Young Girl's Mother Guest Star Melissa George Lauren Reed Guest Star J.J. Abrams Executive Producer John Eisendrath Executive Producer Ken Olin Executive Producer Jeff Pinkner Writer Jack Bender Director