Seth MacFarlane Stan Smith, Roger Voice, Writer Wendy Schaal Francine Smith Voice Rachael MacFarlane Hayley Smith Voice Scott Grimes Steve Smith Voice Dee Bradley Baker Klaus Voice Curtis Armstrong Snot Lonstein Guest Voice Mike Barker Biology Teacher Guest Voice, Writer Chris Cox George W. Bush Guest Voice Carmen Electra Lisa Silver Guest Voice Jeff Fischer Jeff Fischer Guest Voice Mike Henry Jackson Guest Voice Natasha Melnick Hilary Guest Voice Kevin Michael Richardson Principal Lewis Guest Voice André Sogliuzzo Mr. Goodwin Guest Voice Ron Hughart Director Matt Weitzman Writer