Annie Potts Mary Elizabeth "M.E." O'Brien Sims Actor Mae Middleton Mary Elizabeth Actor Lorraine Toussaint Rene Jackson Actor Shari Dyon Perry Rene Actor Donzaleigh Abernathy Sara Jackson Actor John Lafayette James Jackson Actor Christopher Babers Actor Chris Mulkey Colliar Sims Actor Olivia Friedman Kelly Sims Williams Actor Christopher Winsor Davis Sims Actor Nancy McLoughlin Guest Star Elise Shirley Guest Star Richard Biggs Guest Star Andrew McFarlane Guest Star China Shavers Guest Star Al Fann Guest Star Greg Vaughan Guest Star