Kelsey Grammer Mayor Tom Kane Actor Connie Nielsen Meredith Kane Actor Jeff Hephner Ben Zajac Actor Kathleen Robertson Kitty O'Neil Actor Francis Guinan Gov. McCall Cullen Actor Troy Garity Sam Miller Actor Martin Donovan Ezra Stone Actor Hannah Ware Emma Kane Actor Rotimi Darius Morrison Actor Jonathan Groff Ian Todd Guest Star Sanaa Lathan Mona Fredricks Guest Star T.I. Trey Rogers Guest Star Daniel J. Travanti Gerald 'Babe' McGantry Guest Star Amy Morton Catherine Walsh Guest Star Karen Aldridge Dr. Ella Harris Guest Star James Vincent Meredith Alderman Ross Guest Star Danny Goldring Ryan Kavanaugh Guest Star Anthony Mockus Sr. Mayor Rutledge Guest Star Nicole Forester Maggie Zajac Guest Star Jennifer Anglin Nancy Guest Star DuShon Monique Brown Large Inmate Guest Star Hanna Dworkin Upset Mother Guest Star Mary Hollis Inboden Jackie Guest Star Anish Jethmalani Male Nurse Guest Star Howie Johnson Police Officer Guest Star Brian King Chuck Guest Star Elizabeth Laidlaw Linda Driscoll Guest Star Elizabeth Ledo Angry Inmate Guest Star Sandra Marquez Adriana Mata Guest Star Danny McCarthy Rick Mathers Guest Star Richard Ray Perez Ortiz Guest Star Branden Smith Max Harris Guest Star Rebecca Spence Tina Guest Star Craig Spidle Peter Baine Guest Star Phillip Edward Van Lear Alderman Alverson Guest Star Matthew W. Allen Businessman Guest Star