Tom Kapinos Creator, Executive Producer David Duchovny Hank Moody Actor, Executive Producer Natascha McElhone Karen Actor Madeleine Martin Becca Moody Actor Madeline Zima Mia Lewis Actor Evan Handler Charlie Runkle Actor Pamela Adlon Marcy Runkle Actor Rob Lowe Guest Star Maggie Grace Guest Star Stephen Tobolowsky Guest Star Alanna Ubach Guest Star Sarah Wynter Guest Star Jorge Garcia Guest Star Steve Jones Guest Star Meghan Falcone Guest Star Tim Minchin Guest Star Scott Rosendall Guest Star