Gary Sinise Det. Mack "Mac" Taylor Actor Sela Ward Jo Danville Actor Carmine Giovinazzo Det. Danny Messer Actor Hill Harper Dr. Sheldon Hawkes Actor Eddie Cahill Det. Donald Flack, Jr. Actor Anna Belknap Det. Lindsay Monroe Messer Actor A.J. Buckley Adam Ross Actor Robert Joy Dr. Sid Hammerback Actor Natalie Martinez Detective Jamie Lovato Guest Star Stephen Snedden Guest Star Jeff Branson Andy Stein Guest Star Daniel Amerman Justin Vanderheyden Guest Star Tyson Turrou Guest Star Nicole J. Butler Rhonda Reynolds Guest Star Victoria Barabas Reporter Guest Star Miranda Moore Guest Star Brandon Ray Olive Guest Star Bill A. Jones Richard Kemp Guest Star Roy Abramsohn Male Reporter Guest Star Jerry Bruckheimer Executive Producer Carol Mendelsohn Executive Producer Ann Donahue Executive Producer Anthony Zuiker Executive Producer Danny Cannon Executive Producer Andrew Lipsitz Executive Producer Trey Callaway Writer Howard Deutch Director