Gary Sinise Det. Mack "Mac" Taylor Actor Sela Ward Jo Danville Actor Carmine Giovinazzo Det. Danny Messer Actor Hill Harper Dr. Sheldon Hawkes Actor Eddie Cahill Det. Donald Flack, Jr. Actor Anna Belknap Det. Lindsay Monroe Messer Actor A.J. Buckley Adam Ross Actor Robert Joy Dr. Sid Hammerback Actor Natalie Martinez Detective Jamie Lovato Guest Star Myk Watford Guest Star Sam Situmorang Guest Star Kanin Howell Paul Tortucci Guest Star Daniel Roebuck Guest Star Teo Olivares Noah Guest Star Shayla Beesley Abby Guest Star Chasty Ballesteros Rowena Black Guest Star Leif Gantvoort George Guest Star Julie McKinnon A , V Lab Tech Guest Star Jerry Bruckheimer Executive Producer Carol Mendelsohn Executive Producer Ann Donahue Executive Producer Anthony Zuiker Executive Producer Danny Cannon Executive Producer Andrew Lipsitz Executive Producer David Hoselton Writer Alex Zakrzewski Director