Teri Hatcher Susan Mayer Actor Felicity Huffman Lynette Scavo Actor Marcia Cross Bree Hodge Actor Eva Longoria Gabrielle Solis Actor Nicollette Sheridan Edie Britt Actor Brenda Strong Mary Alice Young Actor James Denton Mike Delfino Actor Doug Savant Tom Scavo Actor Ricardo Antonio Chavira Carlos Solis Actor Andrea Bowen Julie Mayer Actor Shawn Pyfrom Andrew Van De Kamp Actor Joy Lauren Danille Van De Kamp Actor Rachel Fox Kayla Huntington Actor Kyle MacLachlan Orson Hodge Actor Dana Delany Katherine Mayfair Actor Lyndsy Fonseca Dylan Mayfair Actor Zane Huett Parker Scavo Actor Brent Kinsman Porter Scavo Actor Shane Kinsman Preston Scavo Actor Nathan Fillion Dr. Adam Mayfair Guest Star Kathryn Joosten Mrs. McCluskey Guest Star Gary Cole Wayne Davis Guest Star Justine Bateman Ellie Leonard Guest Star Tuc Watkins Bob Hunter Guest Star Kevin Rahm Lee McDermott Guest Star Peter Birkenhead Dr. Joshua Dolan Guest Star Billy Gardell Roy Harding Guest Star Rick Otto Detective Paul Bullock Guest Star Bill Smitrovich Reverend Green Guest Star Peggy Blow Fern Parrish Guest Star Lisa Long Irene Semanis Guest Star Wendy Schenker Arresting Police Officer Guest Star Paul Keith Joe Guest Star Michelle Marsh Sheila Guest Star Melody Butiu Nurse #2 Guest Star Sonya Eddy Vanessa Guest Star Kristen O'Meara Griselda Guest Star Leslie Karpman Debbie Guest Star Danny Gurwin Assistant Pastor Guest Star Helen Slayton-Hughes Elderly Woman Guest Star Dale Waddington Nurse Guest Star Mark Brady Jail Cell Officer Guest Star Charles Pratt Jr. Executive Producer Marc Cherry Executive Producer Tom Spezialy Executive Producer Michael Edelstein Executive Producer Bob Daily Writer Matt Berry Writer Bethany Rooney Director