Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Joan Watson Actor Aidan Quinn Captain Thomas Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Talia Balsam Cheryl Gregson Guest Star Sarah Wynter Beth Roney Guest Star Peter Hermann Detective Craig Basken Guest Star Ted King James Monroe Guest Star Armando Riesco Jacob Esparza Guest Star Kathleen Chalfant Mrs. Clennon Guest Star Christopher Burns Coordinating Detective Guest Star Danny Rutigliano Prisoner Guest Star Robert Doherty Executive Producer Carl Beverly Executive Producer Sarah Timberman Executive Producer Craig Sweeny Executive Producer Cathryn Humphris Writer Christine Moore Director