Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Joan Watson Actor Aidan Quinn Captain Thomas Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Nelsan Ellis Shinwell Johnson Actor Ophelia Lovibond Kitty Winter Guest Star Tim Guinee NSA Agent McNally Guest Star Alan Rosenberg Sydney Garber Guest Star Blair Brown Kate Durning Guest Star Marianne Muellerleile Margaret Guest Star Scott Shepherd Anson Gephardt Guest Star Rachel Christopher Receptionist Guest Star Marlie Hall Cable News Anchor Guest Star Connor Bond FBI Agent 1 Guest Star Steve Key FBI Agent 2 Guest Star Jim Piddock Tom Saunders, V.O. Guest Star Robert Doherty Executive Producer, Writer Carl Beverly Executive Producer Sarah Timberman Executive Producer John Polson Executive Producer Jason Tracey Executive Producer, Writer Christine Moore Director