Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Joan Watson Actor Aidan Quinn Captain Thomas Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Desmond Harrington Michael Actor Jordan Gelber ME Hawes Guest Star Erica Hernandez Lauren Wexler Guest Star Ashlie Atkinson Gay Guest Star Jeb Brown Levi Salinger Guest Star Graham Winton Lance Pickering Guest Star Portia Marjorie Guest Star Tony Manna Troy Roselli Guest Star Terence Archie Boss Guest Star Samrat Chakrabarti Vikrant Jindal Guest Star Michele Selene Ang Kelsey Chapman Guest Star Adam Petchel Fred Guest Star Rashad Edwards Security Guard Guest Star Robert Doherty Executive Producer Carl Beverly Executive Producer Sarah Timberman Executive Producer John Polson Executive Producer Jason Tracey Executive Producer