Goran Visnjic Dr. Luka Kovac Actor Maura Tierney Abby Lockhart Actor Mekhi Phifer Dr. Gregory Pratt Actor Parminder Nagra Dr. Neela Rasgotra Actor Linda Cardellini Nurse Samantha Taggart Actor Shane West Actor Scott Grimes Dr. Archie Morris Actor Laura Innes Dr. Kerry Weaver Actor John Stamos Dr. Tony Gates Actor Stanley Tucci Dr. Kevin Moretti Guest Star Chloe Greenfield Sarah Riley Guest Star Malaya Rivera Drew Katey Alvaro Guest Star Troy Evans Frank Martin Guest Star Robert Bagnell Paxton Guest Star Sara Botsford Mrs. Calder Guest Star Stephanie Childers Hilary Guest Star Kyle Davis Kyle Guest Star George Gerdes Jim Riley Guest Star Dave Shalansky Mr. Saltzman Guest Star Christopher Chulack Executive Producer Michael Crichton Executive Producer David Zabel Executive Producer John Wells Executive Producer R. Scott Gemmill Executive Producer