Goran Visnjic Dr. Luka Kovac Actor Maura Tierney Abby Lockhart Actor Mekhi Phifer Dr. Gregory Pratt Actor Parminder Nagra Dr. Neela Rasgotra Actor Linda Cardellini Nurse Samantha Taggart Actor Scott Grimes Dr. Archie Morris Actor John Stamos Dr. Tony Gates Actor Chloe Greenfield Sarah Riley Guest Star Kari Matchett Dr. Skye Wexler Guest Star Adriana Barraza Dolores Salazar Guest Star Leland Orser Dr. Lucien Dubenko Guest Star John Aylward Dr. Donald Anspaugh Guest Star Sam Murphy John Murphy Guest Star Steven Christopher Parker Guest Star Laura Cerón Nurse Chuny Marquez Guest Star Troy Evans Frank Martin Guest Star Gil McKinney Dr. Paul Grady Guest Star Khylan Jones Kiki Guest Star Christopher Chulack Executive Producer Michael Crichton Executive Producer David Zabel Executive Producer John Wells Executive Producer R. Scott Gemmill Executive Producer