Treat Williams Dr. Andrew Brown Actor Gregory Smith Ephram Brown Actor Emily VanCamp Amy Abbott Actor Debra Mooney Edna Abbott Actor John Beasley Irv Harper Actor Vivien Cardone Delia Brown Actor Chris Pratt Bright Abbott Actor Tom Amandes Dr. Harold Abbott Actor Stephanie Niznik Nina Feeney Actor Betty White Guest Star Paul Wesley Guest Star Sarah Lancaster Guest Star Marcia Cross Actor Greg Berlanti Executive Producer Mickey Liddell Executive Producer