Treat Williams Dr. Andrew Brown Actor Gregory Smith Ephram Brown Actor Emily VanCamp Amy Abbott Actor Debra Mooney Edna Abbott Actor John Beasley Irv Harper Actor Vivien Cardone Delia Brown Actor Chris Pratt Bright Abbott Actor Stephanie Niznik Nina Feeney Actor Merrilyn Gann Rose Abbott Actor Tom Amandes Dr. Harold Abbott Actor Scott Wolf Dr. Jake Hartman Actor Sarah Drew Hannah Rogers Actor Jayne Brook Guest Star Keith David Guest Star Gina Ravera Guest Star Justin Baldoni Guest Star Greg Berlanti Executive Producer Mickey Liddell Executive Producer Barbie Kligman Writer David Paymer Director