Kelsey Grammer Dr. Frasier Crane Actor, Executive Producer John Mahoney Martin Crane Actor Jane Leeves Daphne Moon Actor David Hyde Pierce Dr. Niles Crane Actor Peri Gilpin Roz Doyle Actor Adam Arkin Tom Guest Star Dan Butler Bob "Bulldog" Briscoe Guest Star Allison Janney Phyllis Guest Voice Bill Gates Bill Gates Guest Star Patrick Kerr Noel Shempsky Guest Star Tom McGowan Kenny Daly Guest Star Larry Gelbart Joe Guest Voice Jennifer Jason Leigh Estelle Guest Voice Bobby Short Warren Guest Voice David Angell Executive Producer Peter Casey Executive Producer David Lee Executive Producer, Director Mark Reisman Executive Producer Dan O'Shannon Executive Producer Rob Hanning Writer