Kelsey Grammer Dr. Frasier Crane Actor, Executive Producer John Mahoney Martin Crane Actor Jane Leeves Daphne Moon Actor David Hyde Pierce Dr. Niles Crane Actor Peri Gilpin Roz Doyle Actor Millicent Martin Gertrude Moon Guest Star Suzanne Cryer Denise Guest Star Ted King Craig Guest Star Marcia Ann Burrs Aunt Pearl Guest Star Bobby Brewer Curtis Guest Star Brian Cox Harry Moon Guest Star David Angell Executive Producer Peter Casey Executive Producer David Lee Executive Producer Mark Reisman Executive Producer Dan O'Shannon Executive Producer Wil Shriner Director Lori Kirkland Baker Writer