John Francis Daley Sam Weir Actor Linda Cardellini Lindsay Weir Actor Samm Levine Neal Schweiber Actor Martin Starr Bill Haverchuck Actor James Franco Daniel Desario Actor Jason Segel Nick Andopolis Actor Seth Rogen Ken Miller Actor Joe Flaherty Harold Weir Actor Becky Ann Baker Jean Weir Actor Busy Philipps Kim Kelly Guest Star Tom Wilson Coach Ben Fredricks Guest Star Ann Dowd Cookie Kelly Guest Star Sam McMurray Dr. Vic Schweiber Guest Star Chauncey Leopardi Alan White Guest Star Jerry Messing Gordon Crisp Guest Star Judd Apatow Executive Producer Jake Kasdan Director Paul Feig Writer, Producer