Rose McIver Samantha Actor Utkarsh Ambudkar Jay Actor Brandon Scott Jones Isaac Actor Richie Moriarty Pete Actor Danielle Pinnock Alberta Actor Asher Grodman Trevor Actor Román Zaragoza Sasappis Actor Sheila Carrasco Flower Actor Rebecca Wisocky Hetty Actor Devan Chandler Long Thorfinn Actor Betsy Sodaro Nancy Actor Caroline Aaron Carol Guest Star John Hartman Nigel Chessum Actor Puna Patel Bela Guest Star Deniz Akdeniz Chris Actor Tristan D. Lalla Mark Actor Douglas Sills Samuel Actor Cat Lemieux Cholera Victim Cat Actor Stuart Fink Cholera Victim Stuart Actor Nigel Downer Cholera Victim Nigel Actor Joe Port Executive Producer Joe Wiseman Executive Producer Mathew Baynton Executive Producer Jim Howick Executive Producer Simon Farnaby Executive Producer Laurence Rickard Executive Producer Ben Willbond Executive Producer Martha Howe-Douglas Executive Producer Alison Carpenter Executive Producer Debra Hayward Executive Producer Alison Owen Executive Producer Angie Stephenson Executive Producer Trent O'Donnell Director Jay Karas Director Lauren Bridges Writer Talia Bernstein Writer Jude Weng Director John Timothy Writer Christine Gernon Director Trey Kollmer Writer